[Wikipedia] Toxicity: All parts of Datura plants are toxic, containing dangerous levels of tropane alkaloids and may be fatal if ingested by humans and other animals, including livestock and pets. In some places, it is prohibited to buy, sell or cultivate Datura plants. (link added by Mary Ann Machi)

[Cal-IPC] Mexico & Central America native: Datura inoxia (pricklyburr) is a herb (family Solanaceae) with large white flowers, broad leaves and prickly fruits found in the south and central western ranges of California. It is native to Mexico and Central America. It favors dunes and grasslands. It spreads via seed and rhizomes. Seeds are dispersed via ants, birds, animal fur and water. (link added by Mary Ann Machi)